GENERAL INFORMATION
Collaborative Research Centre
TRR 295 ReTune
Our TRR 295 seeks to improve the understanding of the various symptoms of human movement disorders by elucidating symptom-specific neural activity and developing specific treatment strategies for network modulation in common and clinically-relevant neurological diseases. We hypothesize that neuromodulation is a promising tool that can modify network activity and restore motor function by eliminating pathological network activity, augmenting normal interareal communication, or activating compensatory circuits. …
News & Events
Open Positions: Postdoc & PhD student (m/f/d) in Düsseldorf
Nov 1, 2022 | Düsseldorf
Join ReTune to work on MEG based markers of optimized STN‐DBS. Prof. Esther Florin offers a Postdoc and a PhD position. Collaborations within ReTune is anticipated!
Publications
Non-zero mean alpha oscillations revealed with computational model and empirical data
Ongoing oscillations and evoked responses are two main types of neuronal activity obtained with diverse electrophysiological recordings (EEG/MEG/iEEG/LFP). Although typically studied separately, they might in fact be closely related. One possibility to unite them is to demonstrate that neuronal oscillations have non-zero mean which predicts that stimulus- or task-triggered amplitude modulation of oscillations can contribute to the generation of evoked responses. ...
Published: 2022 Jul
No Higher Risk-Seeking Tendencies or Altered Self-Estimation in a Social Decision-Making Task in Patients with Parkinson’s Disease
Alexandra C Zapf, Ann-Kristin Folkerts, Larissa Kahler, Alfons Schnitzler, Paul Reker, Michael T Barbe, Esther Florin, Elke Kalbe
Parkinson's disease (PD) has been associated with a tendency towards more risky decisions. However, the commonly used paradigms typically neglect the social context. Here, we investigated social decision-making and self-estimation in a competitive experimental task. ...
Published: 2022 Jan
Electrophysiological characterization of the hyperdirect pathway and its functional relevance for subthalamic deep brain stimulation
The subthalamic nucleus (STN) receives input from various cortical areas via hyperdirect pathway (HDP) which bypasses the basal-ganglia loop. Recently, the HDP has gained increasing interest, because of its relevance for STN deep brain stimulation (DBS). To understand the HDP's role cortical responses evoked by STN-DBS have been investigated. ...
Published: 2022 Mar
