TRR 295

Publications

Insights and latest results of our research are regularly published in peer-reviewed journals. The majority of our articles are published open access to ensure the availability to a broad audience including affected people and the general lay public.

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Varying patterns of association between cortical large-scale networks and subthalamic nucleus activity in Parkinson’s disease.

Kohl et al. 2026 NPJ Parkinsons Dis.

We analysed simultaneous magnetoencephalography and subthalamic nucleus (STN) local field potential recordings from 27 individuals with Parkinson’s disease, both on and off dopaminergic medication.

StimVision: smartphone video kinematics to optimize DBS programming in Parkinson’s disease. 

Lange, Köberle et al. 2026 NPJ Parkinsons Dis.

Paper of the Month 04/2026

Baseline Cerebral Small Vessel Disease Predicting Long-Term Cognitive Decline in Transient Ischemic Attac Patients.

Roesen et al. 2026 Eur J Neurol.

This study investigated the prevalence of CSVD imaging biomarkers in TIA patients and their association with cognitive performance over 3 years.

The graded effect of propofol in electrophysiology-guided navigation during deep brain stimulation surgery.

Issabenkov et al. 2026 NPJ Parkinsons Dis.

We performed multimodal analysis on 583 microelectrode recordings (MER) from PD patients undergoing DBS surgery under local anesthesia (LA) and GA.

The Virtual Brain links transcranial magnetic stimulation evoked potentials and inhibitory neurotransmitter changes in major depressive disorder.

Hofsähs et al. 2026 Imaging Neurosci (Camb).

Transcranial magnetic stimulation evoked potentials (TEPs) show promise as a biomarker in major depressive disorder (MDD), but the origin of the increased TEP amplitude in these patients remains unclear. Gamma aminobutyric acid (GABA) may be involved, as TEP peak amplitude is known to increase with GABAergic activity in healthy controls. We employed a computational modeling approach to investigate this phenomenon.

Probabilistic mapping of tremor control and gait ataxia risk in deep brain stimulation.

Weigl, Pistorius et al. 2026 J Neural Transm (Vienna).

We analysed long-term tremor and gait outcomes in 73 patients from two DBS centres with chronic bilateral (sub)thalamic DBS, assessed before surgery and at follow-up after 12 months using blinded ratings of standardized video recordings. We evaluated the influence of demographic, clinical, and stimulation parameters and applied voxel-wise probabilistic stimulation mapping to identify anatomical regions associated with tremor suppression and stimulation-induced gait ataxia.
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