Research insights to improve the therapy of brain disorders by the Transregional Collaborative Research Center TRR 295 ReTune, which is funded by the German Research Foundation (DFG).
Many neurological diseases are associated with movement disorders. Neuromodulation, a method that applies therapeutic electric currents or magnetic fields to the brain, has demonstrably helped restore motor deficits in movement-impaired patients. While deep brain stimulation (DBS) is considered the gold standard for treating Parkinson´s disease (PD) and various forms of tremor or dystonia, these therapies are not yet available for many other brain diseases.
In the brain, approximately 86 billion nerve cells interact spatially and temporally to create a highly complex dynamic network whose exact functioning remains one of the great mysteries of brain research. One research focus of the TRR 295 ReTune is to understand the mechanisms and function of dynamic neuronal networks in health and disease in order to retune altered networks by invasive or non-invasive brain stimulation. The aim is to develop innovative neuromodulation systems that respond to specific demands, precisely target individual symptom cycles, and are activated only when disease symptoms occur.
The Collaborative Research Centre TRR 295 ReTune consists of an interdisciplinary team of physicians, neuroscientists, and basic researchers from the Charité – Universitätsmedizin Berlin, Julius-Maximilians-Universität Würzburg, and seven other internationally renowned institutions in Düsseldorf, Potsdam, Leipzig, Rostock, Berlin, Würzburg, and Jerusalem. This multidisciplinary consortium is collaborating on various research projects, each addressing specific aspects of motor network disorders. The joint project is being funded with ten million euros by the German Research Foundation (DFG) for an initial period of four years starting in 2020.
Oct 15, 2024
Jul 24, 2024
Nov 25 & 26, 2024 | Landgut Stober
Sep 27 – Oct 1, 2024 | Philadelphia, PA
September 10, 2024
August 17, 2024
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