Feldmann LK, Kaplan J, de Almeida Marcelino AL, Schulze D, Kühn AA.

Dystonia. 2026 Jun 02. doi: 10.3389/dyst.2026.16304.

Abstract

Accurate subthalamic beta activity could guide deep brain stimulation programming in Parkinson’s disease, but bipolar recordings complicate contact selection. In 39 patients, we validated three methods to estimate pseudo-monopolar beta power. Distance-weighted methods (Euclidean, Strelow) agreed consistently with the externalized “ground-truth” beta distribution. Maximal beta power across 20s windows was more stable in ring than in directional channels. Beta-contacts from all methods aligned with clinically active stimulation contacts one year after surgery.