ReTune Neuroscience Colloquium: Aysegul Gunduz

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September 30, 2021 | 5 pm | Zoom

Simulation on demand: Closing the loop on essential tremor.

Deep brain stimulation (DBS) has been shown to be effective for treating movement disorders, including essential tremor. Most stimulators work in open-loop mode, applying continuous stimulation with no consideration of patients’ symptoms. We developed a closedloop system based on upper limb motor activity detected with a cortical electrode. The system was as effective as the open-loop stimulation while preserving energy. The results suggest that CL-DBS could save energy and possibly reduce side effects associated with continuous DBS.

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